Rho-kinase inhibitor fasudil reduces allergic airway inflammation and mucus hypersecretion by regulating STAT6 and NFκB-Reference-Cited by-同舟云学术

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Rho-kinase inhibitor fasudil reduces allergic airway inflammation and mucus hypersecretion by regulating STAT6 and NFκB

Published:2015-11-19 Issue:12 Volume:45 Page:1812-1822
ISSN:0954-7894
Container-title:Clinical & Experimental Allergy
language:en
Short-container-title:Clin Exp Allergy

Author:

Xie T.¹,Luo GY.²,Zhang Y.¹,Wang X.¹,Wang XY.¹,Wu M.³,Li GP.¹⁴

Affiliation:

1. Inflammations & Allergic Diseases Research Unit; First Affiliated Hospital of Sichuan Medical University; Luzhou Sichuan China

2. Staff Health Clinic; Sichuan Medical University; Luzhou Sichuan China

3. Department of Basic Biomedical Sciences; School of Medicine and Health Sciences; University of North Dakota; Grand Forks ND USA

4. State Key Laboratory of Respiratory Disease for Allergy; School of Medicine; Shenzhen University; Shenzhen Guangdong China

Funder

Chinese National Science Foundation

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cea.12606/fullpdf

Reference43 articles.

1. Treatment of airway mucus hypersecretion;Rogers;Ann Med,2006

2. Mucus hypersecretion in asthma: causes and effects;Evans;Curr Opin Pulm Med,2009

3. Muc5b is required for airway defence;Roy;Nature,2014

4. Interleukin-13-induced mucous metaplasia increases susceptibility of human airway epithelium to rhinovirus infection;Lachowicz-Scroggins;Am J Respir Cell Mol Biol,2010

5. Managing asthma: an evidence-based approach to optimizing inhaled corticosteroid treatment;Fromer;South Med J,2010

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