Therapeutic doses of recombinant factor VIIa in hemophilia generates thrombin in platelet‐dependent and ‐independent mechanisms
Author:
Affiliation:
1. Department of Cellular and Molecular Biology The University of Texas Health Science Center at Tyler Tyler TX USA
2. Coagulation Biology Laboratory Oklahoma Medical Research Foundation Oklahoma City OK USA
Funder
National Heart, Lung, and Blood Institute
Publisher
Wiley
Subject
Hematology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/jth.14881
Reference57 articles.
1. Factor VIIa and its potential therapeutic use in bleeding-associated pathologies
2. Off-Label Use of Recombinant Factor VIIa in U.S. Hospitals: Analysis of Hospital Records
3. Safety profile of recombinant factor VIIa
4. Recombinant factor VIIa: review of efficacy, dosing regimens and safety in patients with congenital and acquired factor VIII or IX inhibitors
5. Complications of recombinant activated human coagulation factor VII
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2. Factor VIIa treatment increases circulating extracellular vesicles in hemophilia patients: Implications for the therapeutic hemostatic effect of FVIIa;Journal of Thrombosis and Haemostasis;2022-08
3. Selective inhibition of activated protein C anticoagulant activity protects against hemophilic arthropathy in mice;Blood;2022-05-05
4. The Reevaluation of Thrombin Time Using a Clot Waveform Analysis;Journal of Clinical Medicine;2021-10-21
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