Delirium detection tools show varying completion rates and positive score rates when used at scale in routine practice in general hospital settings: A systematic review

Author:

Penfold Rose S.1ORCID,Squires Charlotte2ORCID,Angus Alisa2,Shenkin Susan D.1ORCID,Ibitoye Temi3ORCID,Tieges Zoë4ORCID,Neufeld Karin J.5ORCID,Avelino‐Silva Thiago J.6ORCID,Davis Daniel7ORCID,Anand Atul8ORCID,Duckworth Andrew D.9,Guthrie Bruce10ORCID,MacLullich Alasdair M. J.3ORCID

Affiliation:

1. Edinburgh Delirium Research Group, Ageing and Health and Advanced Care Research Centre, Usher Institute University of Edinburgh Edinburgh UK

2. NHS Lothian Edinburgh UK

3. Edinburgh Delirium Research Group, Ageing and Health, Usher Institute University of Edinburgh Edinburgh UK

4. School of Computing, Engineering and Built Environment Glasgow Caledonian University Glasgow UK

5. Department of Psychiatry and Behavioural Neurosciences McMaster University Hamilton Ontario Canada

6. Global Brain Health Institute University of California San Francisco California USA

7. MRC Unit for Lifelong Health and Ageing UCL London UK

8. Centre for Cardiovascular Science University of Edinburgh Edinburgh UK

9. Usher Institute University of Edinburgh Edinburgh UK

10. Advanced Care Research Centre, Usher Institute University of Edinburgh Edinburgh UK

Abstract

AbstractBackgroundMultiple short delirium detection tools have been validated in research studies and implemented in routine care, but there has been little study of these tools in real‐world conditions. This systematic review synthesized literature reporting completion rates and/or delirium positive score rates of detection tools in large clinical populations in general hospital settings.MethodsPROSPERO (CRD42022385166).Medline, Embase, PsycINFO, CINAHL, and gray literature were searched from 1980 to December 31, 2022. Included studies or audit reports used a validated delirium detection tool performed directly with the patient as part of routine care in large clinical populations (n ≥ 1000) within a general acute hospital setting. Narrative synthesis was performed.ResultsTwenty‐two research studies and four audit reports were included. Tools used alone or in combination were the Confusion Assessment Method (CAM), 4 ‘A's Test (4AT), Delirium Observation Screening Scale (DOSS), Brief CAM (bCAM), Nursing Delirium Screening Scale (NuDESC), and Intensive Care Delirium Screening Checklist (ICDSC). Populations and settings varied and tools were used at different stages and frequencies in the patient journey, including on admission only; inpatient, daily or more frequently; on admission and as inpatient; inpatient post‐operatively. Tool completion rates ranged from 19% to 100%. Admission positive score rates ranged from: CAM 8%–51%; 4AT 13%–20%. Inpatient positive score rates ranged from: CAM 2%–20%, DOSS 6%–42%, and NuDESC 5–13%. Postoperative positive score rates were 21% and 28% (4AT). All but two studies had moderate–high risk of bias.ConclusionsThis systematic review of delirium detection tool implementation in large acute patient populations found clinically important variability in tool completion rates, and in delirium positive score rates relative to expected delirium prevalence. This study highlights a need for greater reporting and analysis of relevant healthcare systems data. This is vital to advance understanding of effective delirium detection in routine care.

Funder

Wellcome Trust

Publisher

Wiley

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