Impact of race‐neutral eGFR calculations on African American kidney transplant candidate wait time: A single center retrospective analysis

Author:

Khaim Rafael1ORCID,Todd Rachel1,Rosowicz Andrew1,Shapiro Ron1,Florman Sander1ORCID,Kim‐Schluger Leona1,Tedla Fasika1ORCID

Affiliation:

1. Mount Sinai Recanati/Miller Transplantation Institute Icahn School of Medicine New York New York USA

Abstract

AbstractRace‐inclusive estimated glomerular filtration rate (eGFR) could contribute to racial disparity in access to kidney transplantation. The Organ Procurement and Transplantation Network (OPTN) issued a policy allowing waiting time modification for candidates affected by race‐inclusive eGFR calculations. Implementation of the new OPTN policy at the kidney transplant program of the Mount Sinai Hospital involved review of 921 African American candidates, of whom 240 (26%) candidates gained a median of 1 year and 10 months. The duration of time candidates gained varied from a minimum of 5 days to a maximum of 12 years and 3 months; 45.4% gained at least 2 years, and 12% gained at least 4 years of wait time. Among those who gained wait time, 20 (8.3%) candidates received deceased donor kidney transplants. Candidates who gained wait time had similar sociodemographic characteristics as those who did not, except that the median age for the former was higher by 3 years (59 vs. 56). Our early data suggest that the current policy on waiting time modification for candidates affected by race‐inclusive estimation of GFR has the potential to improve racial disparity in access to kidney transplantation. However, the generalizability of our findings to other centers requires further study.

Publisher

Wiley

Reference14 articles.

1. A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease

2. New Creatinine- and Cystatin C–Based Equations to Estimate GFR without Race

3. OPTN/UNOS.Organ Procurement and Transplantation Network Policies.2023. Accessed August 16 2023.https://optn.transplant.hrsa.gov/media/eavh5bf3/optn_policies.pdf

4. Reconsidering the Consequences of Using Race to Estimate Kidney Function

5. OPTN/UNOS.eGFR Background.2023. Accessed August 16 2023.https://optn.transplant.hrsa.gov/media/3rjiwoka/egfr‐background_01052023.pdf

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1. Care of Adults with Advanced Chronic Kidney Disease;Journal of Clinical Medicine;2024-07-26

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