Safety and pharmacodynamics of intranasal GSK2245035, a TLR7 agonist for allergic rhinitis: A randomized trial

Author:

Ellis A. K.1ORCID,Tsitoura D. C.2,Quint D.2,Powley W.2,Lee L. A.2

Affiliation:

1. Department of Medicine; Queen's University; Kingston Ontario Canada

2. GlaxoSmithKline; Stevenage Hertfordshire UK

Funder

GlaxoSmithKline

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference43 articles.

1. Molecular and cellular mechanisms of allergic disease;Broide;J Allergy Clin Immunol,2001

2. The role of T lymphocytes in asthma;Kay;Chem Immunol Allergy,2006

3. Immune tolerance in allergy;Akdis;Curr Opin Immunol,2009

4. The regulation of allergy and asthma;Umetsu;Immunol Rev,2006

5. Therapeutic manipulation of immune tolerance in allergic disease;Akdis;Nat Rev Drug Discov,2009

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