Mechanisms of intrinsic and acquired resistance to kinase-targeted therapies

Author:

Bagrodia Shubha1,Smeal Tod1,Abraham Robert T.1

Affiliation:

1. Oncology Research Unit; Pfizer Worldwide Research and Development; 10777 Science Center Drive; San Diego; CA; USA

Publisher

Wiley

Subject

Dermatology,General Biochemistry, Genetics and Molecular Biology,Oncology

Reference110 articles.

1. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer;Amado;J. Clin. Oncol.,2008

2. Sorafenib exposure decreases over time in patients with hepatocellular carcinoma;Arrondeau;Invest. New Drugs,2011

3. Activation of tyrosine kinases by mutation of the gatekeeper threonine;Azam;Nat. Struct. Mol. Biol.,2008

4. The three M's: melanoma, microphthalmia-associated transcription factor and microRNA;Bell;Pigment Cell Melanoma Res.,2011

5. Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR;Bell;Nat. Genet.,2005

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3