Deficiency of FHL2 attenuates airway inflammation in mice and genetic variation associates with human bronchial hyper-responsiveness

Author:

Kurakula K.1,Vos M.1,Logiantara A.2,Roelofs J. J. T. H.3,Nieuwenhuis M. A.4,Koppelman G. H.5,Postma D. S.4,Brandsma C. A.6,Sin D. D.78,Bossé Y.910,Nickle D. C.1112,van Rijt L. S.2,de Vries C. J. M.1

Affiliation:

1. Deartment of Medical Biochemistry; Academic Medical Center; University of Amsterdam; Amsterdam The Netherlands

2. Department of Experimental Immunology; Academic Medical Center; University of Amsterdam; Amsterdam The Netherlands

3. Department of Pathology; Academic Medical Center; University of Amsterdam; Amsterdam The Netherlands

4. University of Groningen; University Medical Center Groningen; Department of Pulmonology; GRIAC Research Institute; Groningen The Netherlands

5. University of Groningen; University Medical Center Groningen; Department of Pediatric Pulmonology; Beatrix Children's Hospital; GRIAC Research Institute; Groningen The Netherlands

6. University of Groningen; University Medical Center Groningen; Department of Pathology and Medical Biology; GRIAC Research Institute; Groningen The Netherlands

7. The University of British Columbia James Hogg Research Laboratory; St Paul's Hospital; Vancouver Canada

8. Respiratory Division; Department of Medicine; University of British Columbia; Vancouver Canada

9. Department of Molecular Medicine; Laval University; Quebec City Canada

10. Institut Universitaire de Cardiologie et de Pneumologie de Quebec; Laval University; Quebec City Canada

11. Genetics; Rosetta Inpharmatics; Merck Seattle WA USA

12. Merck Research Laboratories; Boston MA USA

Funder

BioMedical Materials Institute

Dutch Ministry of Economic Affairs

Dutch Heart Foundation

Netherlands Asthma Foundation Grants

Universitair Medisch Centrum Groningen

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

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