Diffuse traumatic axonal injury in mice induces complex behavioural alterations that are normalized by neutralization of interleukin-1β

Author:

Ekmark-Lewén Sara1,Flygt Johanna1,Fridgeirsdottir Gudrun A.1,Kiwanuka Olivia1,Hånell Anders1,Meyerson Bengt J.2,Mir Anis K.3,Gram Hermann3,Lewén Anders1,Clausen Fredrik1,Hillered Lars1,Marklund Niklas14

Affiliation:

1. Department of Neuroscience, Neurosurgery; Uppsala University; Uppsala Sweden

2. Department of Neuroscience, Pharmacology; Biomedical Centre; Uppsala University; Uppsala Sweden

3. Novartis Institutes of Biomedical Research; Basel Switzerland

4. Department of Neurosurgery; Uppsala University Hospital; Ing 85, 2 tr SE-756 55 Uppsala Sweden

Funder

Vetenskapsrådet

Akademiska Sjukhuset

The Selander Foundation

Åhlén-stiftelsen

Publisher

Wiley

Subject

General Neuroscience

Reference90 articles.

1. Axonal injury in falls;Abou-Hamden;J. Neurotraum.,1997

2. Diffuse axonal injury in head injury: definition, diagnosis and grading;Adams;Histopathology,1989

3. Interleukin-1 and neuronal injury;Allan;Nat. Rev. Immunol.,2005

4. Cognitive deficits after traumatic coma;Azouvi;Prog. Brain Res.,2009

5. Long-term neurologic outcomes after traumatic brain injury;Bazarian;J. Head Trauma Rehab.,2009

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