At the bench: the key role of PK-PD modelling in enabling the early discovery of biologic therapies
Author:
Affiliation:
1. Clinical Pharmacology & DMPK; MedImmune plc; Granta Park Cambridge CB21 6GH UK
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12225/fullpdf
Reference20 articles.
1. Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development;Peck;Clin Pharmacol Ther,1992
2. Model-based drug development;Lalonde;Clin Pharmacol Ther,2007
3. Concepts and challenges in quantitative pharmacology and model-based drug development;Zhang;AAPS J,2008
4. Trial watch: phase III and submission failures: 2007-2010;Arrowsmith;Nat Rev Drug Discov,2011
5. Recent advances in fragment-based QSAR and multi-dimensional QSAR methods;Myint;Int J Mol Sci,2010
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