Pharmacokinetics and distribution in interstitial and pulmonary epithelial lining fluid of danofloxacin in ruminant and preruminant calves

Author:

Mzyk D. A.1,Baynes R. E.1,Messenger K. M.2ORCID,Martinez M.3,Smith G. W.1

Affiliation:

1. Department of Population Health and Pathobiology and the Food Animal Residue Avoidance; Depletion Program; College of Veterinary Medicine; North Carolina State University; Raleigh NC USA

2. Department of Molecular Biomedical Sciences; College of Veterinary Medicine; North Carolina State University; Raleigh NC USA

3. US Food and Drug Administration; Center for Veterinary Medicine; Office of New Animal Drug Evaluation; Rockville MD USA

Publisher

Wiley

Subject

General Veterinary,Pharmacology

Reference53 articles.

1. Pharmacodynamics of fluoroquinolones against Streptococcus pneumoniae in patients with community-acquired respiratory tract infections;Ambrose;Antimicrobial Agents and Chemotherapy,2001

2. Pharmacodynamics of the new fluoroquinolone gatifloxacin in murine thigh and lung infection models;Andes;Antimicrobial Agents and Chemotherapy,2002

3. Lung-tissue concentrations and plasma pharmacokinetics of danofloxacin in calves with acute pneumonia;Apley;Veterinary Sciences,1993

4. Pulmonary disposition of antimicrobial agents: in vivo observations and clinical relevance;Baldwin;Antimicrobial Agents and Chemotherapy,1992

5. Retention of quinolones on human serum albumin and alpha1-acid glycoprotein HPLC columns: relationships with different scales of lipophilicity;Barbato;European Journal of Pharmaceutical Science,2007

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