Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging-Reference-Cited by-同舟云学术

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Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging

Published:2017-03-19 Issue:3 Volume:16 Page:551-563
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Davis Hannah M.¹,Pacheco-Costa Rafael¹,Atkinson Emily G.¹,Brun Lucas R.¹,Gortazar Arancha R.²,Harris Julia¹,Hiasa Masahiro³,Bolarinwa Surajudeen A.¹,Yoneda Toshiyuki³,Ivan Mircea³,Bruzzaniti Angela⁴,Bellido Teresita¹⁵⁶,Plotkin Lilian I.¹⁶

Affiliation:

1. Department of Anatomy & Cell Biology; Indiana University School of Medicine; Indianapolis IN USA

2. Instituto de Medicina Molecular Aplicada; Facultad de Medicina; Universidad San Pablo-CEU; Madrid Spain

3. Division of Hematology/Oncology; Department of Internal Medicine; Indiana University School of Medicine; Indianapolis IN USA

4. Department of Oral Biology; Indiana University School of Dentistry; Indianapolis IN USA

5. Division of Endocrinology; Department of Internal Medicine; Indiana University School of Medicine; Indianapolis IN USA

6. Roudebush Veterans Administration Medical Center; Indianapolis IN USA

Funder

National Institutes of Health

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Brazil

Life-Health Sciences Internship Program

Indiana University-Purdue University Indianapolis

School of Medicine, Indiana University

NIH-NHLBI

Universidad Nacional de Rosario

Publisher

Wiley

Subject

Cell Biology,Ageing

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/acel.12586/fullpdf

Reference55 articles.

1. Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss;Aguirre;J. Bone Min. Res.,2006

2. Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription;Almeida;J. Biol. Chem.,2007a

3. Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids;Almeida;J. Biol. Chem.,2007b

4. Functional expression in xenopus oocytes of gap-junctional hemichannels formed by a cysteine-less connexin 43;Bao;J. Biol. Chem.,2004

5. Connexin43 interacts with βarrestin: a pre-requisite for osteoblast survival induced by parathyroid hormone;Bivi;J. Cell. Biochem.,2011

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