Tanshinones that selectively block the collagenase activity of cathepsin K provide a novel class of ectosteric antiresorptive agents for bone

Author:

Panwar Preety123,Law Simon123,Jamroz Andrew13,Azizi Pouya3,Zhang Dongwei14,Ciufolini Marco5,Brömme Dieter123ORCID

Affiliation:

1. Department of Oral Biological and Medical Sciences, Faculty of Dentistry; University of British Columbia; Vancouver BC Canada

2. Centre for Blood Research; Vancouver BC Canada

3. Department of Biochemistry and Molecular Biology, Faculty of Medicine; University of British Columbia; Vancouver BC Canada

4. Diabetes Research Centre; Beijing University of Chinese Medicine; Beijing China

5. Department of Chemistry; University of British Columbia; Vancouver BC Canada

Funder

Canadian Institutes of Health Research

Canadian Institutes of Health Research grants

National Natural Science Foundation of China

Publisher

Wiley

Subject

Pharmacology

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