Dual enigma of somatic hypermutation of immunoglobulin variable genes: targeting and mechanism
Author:
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1600-065X.1998.tb01432.x/fullpdf
Reference33 articles.
1. Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response.
2. Differences between germ-line and rearranged immunoglobulin Vκ coding sequences suggest a localized mutation mechanism
3. Antibody diversity: Somatic hypermutation of rearranged VH genes
4. Clusters of point mutations are found exclusively around rearranged antibody variable genes.
5. Somatic Mutation in Anti-Phosphorylcholine Antibodies
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