The Acute Effect in Rats of 3, 4-Methylenedioxyethamphetamine (MDEA, “Eve”) on Body Temperature and Long Term Degeneration of 5-HT Neurones in Brain: A Comparison with MDMA (“Ecstasy”)
Author:
Publisher
Wiley
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1600-0773.1999.tb01492.x/fullpdf
Reference26 articles.
1. Oral administration of 3, 4-methylenedioxymethamphetamine (MDMA) produces selective serotonergic depletion in the non-human primate;Ali;Neurotoxicol Teratol.,1993
2. Age dependent sensitivity of rats to the long term effects of the serotonergic neurotoxicant (+)-3, 4-methylenedioxymethamphetamine (MDMA) correlates with the magnitude of the MDMA-induced thermal response;Broening;J. Pharmacol. Exp. Therap.,1995
3. In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA (“Ecstasy”) and p-chloroamphetamine but not the degeneration following fenfluramine;Colado;Brit. J. Pharmacol.,1997
4. The hyperthermic and neurotoxic effects of ‘Ecstasy’ (MDMA) and 3, 4-methylenedioxy-amphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metaboliser phenotype;Colado;Brit. J. Pharmacol.,1995
5. Eve” and “Ecstasy”. A report of five deaths associated with the use of MDEA and MDMA;Dowling;JAMA,1987
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