Liver Damage Induced by Bile Duct Ligation Affects CYP Isoenzymes Differently in Rats

Author:

Tateishi Tomonori,Watanabe Minoru,Nakura Hironori,Tanaka Masami,Kumai Toshio,Kobayashi Shinichi

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology

Reference19 articles.

1. Regulation of renal cytochrome P-450. Effects of two-thirds hepatectomy, cholestasis, biliary cirrhosis and post-necrotic cirrhosis on hepatic and renal microsomal enzymes;Babany;Biochem. Pharmacol.,1985

2. Metabolism of antipyrine in vivo in two rat models of liver cirrhosis. Its relationship to intrinsic clearance in vino and microsomal membrane lipid composition;Butner;Biochem. Pharmacol.,1993

3. Downregulation of male-specific cytochrome P450s 2C11 and 3A2 in bile duct-ligated male rats: importance to reduced hepatic content of cytochrome P450 in cholestasis;Chen;Hepatology,1995

4. N4-hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes;Cribb;Drag Metab. Dispos.,1995

5. Differential alterations of cytochrome P450 proteins in livers from patients with severe chronic liver disease;George;Hepatology,1995

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