In Vivo Pharmacokinetics of Felodipine Predicted from in Vitro Studies in Rat, Dog and Man

Author:

Bäärnhielm C.,Dahlbäck H.,Skånberg I.

Publisher

Wiley

Subject

Pharmacology,Toxicology

Reference28 articles.

1. Determination of felodipine in plasma by capillary gas chromatography with electron capture detection;Ahnoff;J. Pharm. Biomed. Analys,1984

2. Hepatic drug transport in the rat. A comparison between isolated hepatocytes, the isolated perfused liver and the liver in vivo;Blom;Biochem. Pharmacol.,1982

3. Human cytochromes P-450;Boobis;Xenobiotica,1984

4. Cytochrome P-450-dependent oxidation of felodipine- a 1,4-dihy-dropyridine- to the corresponding pyridine;Bäärnhielm;Xenobiotica,1984

5. Phenytoin metabolism in the rat. Pharmacokinetic correlation between in vitro hepatic microsomal enzyme activity and in vivo elimination kinetics;Collins;Drug Metab. Dispos.,1978

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