The Selective Cardiac Late Sodium Current Inhibitor GS-458967 Suppresses Autonomically Triggered Atrial Fibrillation in an Intact Porcine Model
Author:
Affiliation:
1. Beth Israel Deaconess Medical Center; Boston Massachusetts USA
2. Faculdade de Medicina da Universidade de São Paulo; São Paulo Brazil
3. Harvard Medical School; Boston Massachusetts USA
4. Gilead Sciences, Inc; Foster City California USA
Funder
Science without Borders" (CAPES of the Brazilian Federal Government) and Harvard University's David Rockefeller Center for Latin American Studies.
Gilead Sciences, Inc.
Publisher
Wiley
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jce.12824/fullpdf
Reference30 articles.
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3. Ranolazine exerts potent effects on atrial electrical properties and abbreviates atrial fibrillation duration in the intact porcine heart;Kumar;J Cardiovasc Electrophysiol,2009
4. Antifibrillatory effect of ranolazine during severe coronary stenosis in the intact porcine model;Nieminen;Heart Rhythm,2011
5. A TTX-sensitive resting Na+ permeability contributes to the catecholaminergic automatic activity in rat pulmonary vein;Malécot;J Cardiovasc Electrophysiol,2015
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