Intra-Amniotic Administration of HMGB1 Induces Spontaneous Preterm Labor and Birth

Author:

Gomez-Lopez Nardhy123,Romero Roberto1456,Plazyo Olesya12,Panaitescu Bogdan7,Furcron Amy E.12,Miller Derek123,Roumayah Tamara1,Flom Emily1,Hassan Sonia S.12

Affiliation:

1. Perinatology Research Branch; Program for Perinatal Research and Obstetrics; Division of Intramural Research; Eunice Kennedy Shriver National Institute of Child Health and Human Development; NICHD/NIH/DHHS; Bethesda, MD, and Detroit MI USA

2. Department of Obstetrics and Gynecology; Wayne State University School of Medicine; Detroit MI USA

3. Department of Immunology and Microbiology; Wayne State University School of Medicine; Detroit MI USA

4. Department of Obstetrics and Gynecology; University of Michigan; Ann Arbor MI USA

5. Department of Epidemiology and Biostatistics; Michigan State University; East Lansing MI USA

6. Center for Molecular Medicine and Genetics; Wayne State University; Detroit MI USA

7. Department of Pediatrics; Neonatology Division; Wayne State University School of Medicine; Detroit MI USA

Publisher

Wiley

Subject

Obstetrics and Gynecology,Reproductive Medicine,Immunology,Immunology and Allergy

Reference17 articles.

1. Epidemiology and causes of preterm birth;Goldenberg;Lancet,2008

2. Preterm labor: one syndrome, many causes;Romero;Science,2014

3. Prevalence and clinical significance of sterile intra-amniotic inflammation in patients with preterm labor and intact membranes;Romero;Am J Reprod Immunol,2014

4. Sterile intra-amniotic inflammation in asymptomatic patients with a sonographic short cervix: prevalence and clinical significance;Romero;J Matern Fetal Neonatal Med,2014

5. Sterile and microbial-associated intra-amniotic inflammation in preterm prelabor rupture of membranes;Romero;J Matern Fetal Neonatal Med,2015

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