Effect of sorbitol, single, and multidose activated charcoal administration on carprofen absorption following experimental overdose in dogs

Author:

Koenigshof Amy M.1,Beal Matthew W.1,Poppenga Robert H.2,Jutkowitz L. Ari1

Affiliation:

1. Department of Small Animal Clinical Sciences, College of Veterinary Medicine; Michigan State University; East Lansing MI

2. the Department of Molecular Biosciences, California Animal Health and Food Safety Laboratory; University of California-Davis; Davis CA

Funder

Companion Animal Fund Michigan State University

Publisher

Wiley

Subject

General Veterinary

Reference18 articles.

1. Position paper: single-dose activated charcoal;Chyka;Clin Toxicol (Philadel),2005

2. Evaluation of adverse effects of long-term orally administered carprofen in dogs;Raekallio;J Am Vet Med Assoc,2006

3. Biopharmaceutical evaluation of carprofen following single intravenous, oral, and rectal doses in dogs;Schmitt;Biopharm Drug Dispos,1990

4. Enantioselectivity of the enterohepatic recycling of carprofen in the dog;Priymenko;Drug Metab Dispos,1998

5. Effects of urine alkalization and activated charcoal on the pharmacokinetics of orally administered carprofen in dogs;Raekallio;Am J Vet Res,2007

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