Corticosteroid insensitive alveolar macrophages from asthma patients; synergistic interaction with a p38 mitogen-activated protein kinase (MAPK) inhibitor-Reference-Cited by-同舟云学术

Corticosteroid insensitive alveolar macrophages from asthma patients; synergistic interaction with a p38 mitogen-activated protein kinase (MAPK) inhibitor

Published:2015-04-22 Issue:5 Volume:79 Page:756-766
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Lea Simon¹,Harbron Chris²,Khan Naimat¹,Booth George¹,Armstrong Jane¹,Singh Dave¹

Affiliation:

1. Manchester Academic Health Science Centre; University Hospital South Manchester NHS Foundation Trust; NIHR South Manchester Respiratory and Allergy Clinical Research Facility; The University of Manchester; Manchester M23 9LT UK

2. CH Discovery Statistics; AstraZeneca; Alderley Park Macclesfield Cheshire SK10 4TG UK

Funder

AstraZeneca

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12536/fullpdf

Reference26 articles.

1. Steroid resistance in asthma: mechanisms and treatment options;Adcock;Curr Allergy Asthma Rep,2008

2. p38-dependent marking of inflammatory genes for increased NF-kappa B recruitment;Saccani;Nat Immunol,2002