Cytochrome P450 Induction and Xeno-Sensing Receptors Pregnane X Receptor, Constitutive Androstane Receptor, Aryl Hydrocarbon Receptor and Peroxisome Proliferator-Activated Receptor α at the Crossroads of Toxicokinetics and Toxicodynamics

Author:

Hakkola Jukka12,Bernasconi Camilla3,Coecke Sandra3,Richert Lysiane4,Andersson Tommy B.56,Pelkonen Olavi12

Affiliation:

1. Research Unit of Biomedicine, Pharmacology and Toxicology; Faculty of Medicine; University of Oulu; Oulu Finland

2. Medical Research Center Oulu; University of Oulu; Oulu Finland

3. European Commission Joint Research Centre; EURL ECVAM; Ispra Italy

4. KaLy-Cell; Plobsheim France

5. Drug Metabolism and Pharmacokinetics; Cardiovascular and Metabolic Diseases; IMED Biotech Unit; AstraZeneca; Gothenburg Sweden

6. Department of Physiology and Pharmacology; Section of Pharmacogenetics; Karolinska Institutet; Stockholm Sweden

Funder

Academy of Finland

Novo Nordisk Fonden

Diabetes Research Foundation

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Reference66 articles.

1. The metabolism of methylated aminoazo dyes. V. Evidence for induction of enzyme synthesis in the rat by 3-methylcholanthrene;Conney;Cancer Res,1956

2. Substrate-induced synthesis and other properties of benzopyrene hydroxylase in rat liver;Conney;J Biol Chem,1957

3. Die beschleunigung der evipan oxydation und der methylierung von methyl-aminoantipyrin durch barbiturate;Remmer;Arch Exp Pathol Pharmakol,1959

4. Enzyminduktion und vermehrung von endoplasmatischem reticulum in der leberzelle während der behandlung mit phenobarbital (Luminal);Remmer;Klin Wochenschr,1963

5. Adverse outcome pathways as tools to assess drug-induced toxicity;Vinken;Methods Mol Biol,2016

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