Expression of β -Adrenoceptor Subtypes in Urothelium, Interstitial Cells and Detrusor of the Human Urinary Bladder

Author:

OTSUKA Atsushi,KAWASAKI Hideya,MATSUMOTO Rikiya,SHINBO Hitoshi,KURITA Yutaka,IWASHITA Toshihide,OZONO Seiichiro

Funder

Ministry of Education, Culture, Sports, Science and Technology, Japan

Publisher

Wiley

Subject

Urology,Neurology

Reference33 articles.

1. Evidence for β3-adrenoceptor subtypes in relaxation of the human urinary bladder detrusor: analysis by molecular biological and pharmacological methods;Takeda;J Pharmacol Exp Ther,1999

2. Functional and molecular biological evidence for a possible β3- adrenoceptor in the human detrusor muscle;Igawa;Br J Pharmacol,1999

3. Effect of (R)-2-(2-aminothia zol-4-yl)-4’-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl} ace tanilide (YM178), a novel selective β3- adrenoceptor agonist, on bladder function;Takasu;J Pharmacol Exp Ther,2007

4. Effects of a novel β3- adrenoceptor agonist, AJ-9677, on relaxation of the detrusor muscle: an in vitro study;Otsuka;Int J Urol,2008

5. Clinical proof of concept study (BLOSSOM) shows novel β3 adrenoceptor agonist YM178 is effective and well tolerated in the treatment of symptoms of overactive bladder;Chapple;Eur Urol Suppl,2008

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