ImmTAC/Anti-PD-1 antibody combination to enhance killing of cancer cells by reversing regulatory T-cell-mediated immunosuppression

Author:

Zhang Huanling12ORCID,Li Yanyan12,Liu Xiaoping2,Liang Zhaoduan2,Yan Mengyong3,Liu Qiang2,Chen Anan2,Bao Yifeng2,Zhou Chengzhi4,Li Shiyue4,Yee Cassian5,Li Yi23

Affiliation:

1. School of Life Sciences; University of Science and Technology of China; Hefei Anhui China

2. State Key Laboratory of Respiratory Disease; Guangzhou Institutes of Biomedicine and Health; Chinese Academy of Sciences; Guangzhou Guangdong China

3. XiangXue Life Sciences Research Centre; XiangXue Pharmaceutical Co. Ltd; Guangzhou Guangdong China

4. State Key Laboratory of Respiratory Disease; National Clinical Research Centre for Respiratory Disease; Guangzhou Institutes of Respiratory Disease; The First Affiliated Hospital of Guangzhou Medical University; Guangzhou Guangdong China

5. Department of Melanoma Medical Oncology and Department of Immunology; MD Anderson Cancer Center; Houston TX USA

Funder

Guangzhou Science Technology and Innovation Commission Project Grants

The National key R&D Programme

Guangzhou Science and Technology Program key projects

National Natural Science Foundation of China

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

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