TET proteins and 5-methylcytosine oxidation in hematological cancers

Author:

Ko Myunggon1,An Jungeun1,Pastor William A.1,Koralov Sergei B.2,Rajewsky Klaus3,Rao Anjana145

Affiliation:

1. Division of Signaling and Gene Expression; La Jolla Institute for Allergy and Immunology; La Jolla CA USA

2. Department of Pathology; New York University School of Medicine; New York NY USA

3. Max-Delbrück Centre for Molecular Medicine; Berlin Germany

4. Department of Pharmacology and Moores Cancer Center; University of California at San Diego; La Jolla CA USA

5. Sanford Consortium for Regenerative Medicine; La Jolla CA USA

Funder

National Institutes of Health

California Institute for Regenerative Medicine

Leukemia and Lymphoma Society

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference179 articles.

1. DNA methylation patterns and epigenetic memory;Bird;Genes Dev,2002

2. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1;Tahiliani;Science,2009

3. Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids;Iyer;Cell Cycle,2009

4. LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23);Ono;Cancer Res,2002

5. TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23);Lorsbach;Leukemia,2003

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