Modifiable factors to prevent severe hypoglycaemic and diabetic ketoacidosis presentations in people with type 1 diabetes

Author:

Tamsett Zacchary1ORCID,James Steven12ORCID,Brown Fran3ORCID,O'Neal David N.145ORCID,Ekinci Elif I.156ORCID

Affiliation:

1. Department of Medicine University of Melbourne Parkville Victoria Australia

2. School of Health University of the Sunshine Coast Petrie Queensland Australia

3. Melbourne Diabetes Education and Support Heidelberg Heights Victoria Australia

4. Department of Endocrinology and Diabetes St Vincent's Hospital Fitzroy Victoria Australia

5. Australian Centre for Accelerating Diabetes Innovations University of Melbourne Parkville Victoria Australia

6. Department of Endocrinology Austin Health Heidelberg Victoria Australia

Abstract

AbstractAimsIn tackling rising diabetes‐related emergencies, the need to understand and address emergency service usage by people with type 1 diabetes is vital. This review aimed to quantify current trends in presentations for type 1 diabetes‐related emergencies and identify public health strategies that reduce the frequency of diabetes‐related emergencies and improve glycaemic management.MethodsMedline (OVID), Cochrane and CINAHL were searched for studies published between 2000 and 2023, focusing on people with type 1 diabetes, severe hypoglycaemia and/or diabetic ketoacidosis, and ambulance and/or emergency department usage. There were 1313 papers identified, with 37 publications meeting review criteria.ResultsThe incidence of type 1 diabetes‐related emergencies varied from 2.4 to 14.6% over one year for hypoglycaemic episodes, and between 0.07 and 11.8 events per 100 person‐years for hyperglycaemic episodes. Notably, our findings revealed that ongoing diabetes education and the integration of diabetes technology, such as continuous glucose monitoring and insulin pump therapy, significantly reduced the incidence of these emergencies. However, socio‐economic disparities posed barriers to accessing these technologies, subsequently shifting the cost to emergency healthcare and highlighting the need for governments to consider subsidising these technologies as part of preventative measures.ConclusionsImproving access to continuous glucose monitoring and insulin pump therapy, in combination with ongoing diabetes education focusing on symptom recognition and early management, will reduce the incidence of diabetes‐related emergencies. Concurrent research assessing emergency healthcare usage patterns during the implementation of such measures is essential to ensure these are cost‐effective.

Publisher

Wiley

Reference63 articles.

1. Type 1 diabetes mellitus

2. International Diabetes Federation.IDF diabetes atlas 10th edn.https://www.diabetesatlas.org

3. Australian Bureau of Statistics.Diabetes.https://www.abs.gov.au/statistics/health/health‐conditions‐and‐risks/diabetes/latest‐release

4. IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045

5. Utilisation of emergency medical services for severe hypoglycaemia: An unrecognised health care burden

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