Poorly differentiated chordoma with loss of SMARCB1/INI1 expression in pediatric patients: A report of two cases and review of the literature

Author:

Cha Yoon Jin1ORCID,Hong Chang-Ki2,Kim Dong-Seok3,Lee Seung-Koo4,Park Hyeon Jin5,Kim Se Hoon6

Affiliation:

1. Department of Pathology; Gangnam Severance Hospital, Yonsei University College of Medicine; Seoul South Korea

2. Department of Neurosurgery; Gangnam Severance Hospital, Yonsei University College of Medicine; Seoul South Korea

3. Department of Pediatric Neurosurgery; Severance Children's Hospital, Yonsei University College of Medicine; Seoul South Korea

4. Department of Radiology; Severance Hospital, Yonsei University College of Medicine; Seoul South Korea

5. Center for Pediatric Cancer; National Cancer Center; Goyang South Korea

6. Department of Pathology; Severance Hospital, Yonsei University College of Medicine; Seoul South Korea

Publisher

Wiley

Subject

Clinical Neurology,General Medicine,Pathology and Forensic Medicine

Reference21 articles.

1. Chordoma in childhood and adolescence. A clinicopathologic analysis of 12 cases;Coffin;Arch Pathol Lab Med,1993

2. Clinical and pathologic review of 48 cases of chordoma;Rich;Cancer,1985

3. Base of skull chordomas in children and adolescents: A clinicopathologic study of 73 cases;Hoch;Am J Surg Pathol,2006

4. Loss of SMARCB1/INI1 expression in poorly differentiated chordomas;Mobley;Acta Neuropathol,2010

5. Poorly differentiated chordoma with SMARCB1/INI1 loss: A distinct molecular entity with dismal prognosis;Hasselblatt;Acta Neuropathol,2016

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