GBT 440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half‐life in a murine model of sickle cell disease-Reference-Cited by-同舟云学术

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GBT 440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half‐life in a murine model of sickle cell disease

Published:2016-07-05 Issue:1 Volume:175 Page:141-153
ISSN:0007-1048
Container-title:British Journal of Haematology
language:en
Short-container-title:Br J Haematol

Author:

Oksenberg Donna¹,Dufu Kobina¹,Patel Mira P.¹^ORCID,Chuang Chihyuan²,Li Zhe¹,Xu Qing¹,Silva‐Garcia Abel¹,Zhou Chengjing³,Hutchaleelaha Athiwat¹,Patskovska Larysa⁴,Patskovsky Yury⁴,Almo Steven C.⁴,Sinha Uma¹,Metcalf Brian W.¹,Archer David R.³^ORCID

Affiliation:

1. Global Blood Therapeutics Inc. South San Francisco CA USA

2. Cytokinetics South San Francisco CA USA

3. Department of Pediatrics Aflac Cancer and Blood Disorders Center Emory University School of Medicine Atlanta GA USA

4. Albert Einstein College of Medicine Bronx NY USA

Funder

Global Blood Therapeutics, Inc.

Publisher

Wiley

Subject

Hematology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.14214

Reference42 articles.

1. 5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells

2. Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin

3. Kinetics of the polymerization of hemoglobin in high and low phosphate buffers;Adachi K.;Blood Cells,1982

4. Fetal hemoglobin in sickle cell anemia

5. Tucaresol increases oxygen affinity and reduces haemolysis in subjects with sickle cell anaemia

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