Epidemiology of aplasia cutis congenita: A population‐based study in Europe

Author:

Coi Alessio1ORCID,Barisic Ingeborg2,Garne Ester3,Pierini Anna14,Addor Marie‐Claude5,Aizpurua Atxega Amaia6,Ballardini Elisa7,Braz Paula8,Broughan Jennifer M.9,Cavero‐Carbonell Clara10,de Walle Hermien E. K.11,Draper Elizabeth S.12,Gatt Miriam13,Häusler Martin14,Kinsner‐Ovaskainen Agnieszka15,Kurinczuk Jennifer J.16,Lelong Nathalie17,Luyt Karen18,Mezzasalma Lorena1,Mullaney Carmel19,Nelen Vera20,Odak Ljubica2,O'Mahony Mary T.21,Perthus Isabelle22,Randrianaivo Hanitra23,Rankin Judith924,Rissmann Anke25,Rouget Florence26,Schaub Bruno27,Tucker David28,Wellesley Diana29,Wiśniewska Katarzyna30,Yevtushok Lyubov31,Santoro Michele1

Affiliation:

1. Unit of Epidemiology of Rare Diseases and Congenital Anomalies, Institute of Clinical Physiology National Research Council Pisa Italy

2. Children's Hospital Zagreb, Centre of Excellence for Reproductive and Regenerative Medicine Medical School University of Zagreb Zagreb Croatia

3. Department of Paediatrics and Adolescent Medicine, Lillebaelt Hospital University Hospital of Southern Denmark Kolding Denmark

4. Fondazione Toscana Gabriele Monasterio Pisa Italy

5. Department of Woman‐Mother‐Child University Medical Center CHUV Lausanne Switzerland

6. Public Health Division of Gipuzkoa Biodonostia Research Institute Donostia‐San Sebastian Spain

7. Neonatal Intensive Care Unit, Paediatric Section, IMER Registry (Emilia Romagna Registry of Birth Defects), Department of Medical Sciences University of Ferrara Ferrara Italy

8. Epidemiology Department National Institute of Health Doutor Ricardo Jorge Lisbon Portugal

9. National Congenital Anomaly and Rare Disease Registration Service, National Disease Registration Service, NHS Digital Leeds UK

10. Rare Diseases Research Unit Foundation for the Promotion of Health and Biomedical Research in the Valencian Region Valencia Spain

11. Department of Genetics, University Medical Center Groningen University of Groningen Groningen The Netherlands

12. Department Health Sciences, College of Life Sciences University of Leicester Leicester UK

13. Malta Congenital Anomalies Registry, Directorate for Health Information and Research G'Mangia Malta

14. Medical University of Graz Graz Austria

15. European Commission, Joint Research Centre (JRC) Ispra Italy

16. National Perinatal Epidemiology Unit, Nuffield Department of Population Health University of Oxford Oxford UK

17. Université Paris Cité, Inserm, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé Paris France

18. South West Congenital Anomaly Register, Bristol Medical School University of Bristol Bristol UK

19. Department of Public Health, HSE South East, Lacken Kilkenny Ireland

20. Provincial Institute of Hygiene Antwerp Belgium

21. Department of Public Health, HSE South (Cork & Kerry) Cork Ireland

22. Auvergne Registry of Congenital Anomalies (CEMC‐Auvergne), Department of Clinical Genetics, Centre de Référence des Maladies Rares University Hospital of Clermont‐Ferrand Clermont‐Ferrand France

23. Register of Congenital Malformations Isle of Reunion Island, CHU St Pierre, la Reunion Reunion France

24. Population Health Sciences Institute Newcastle University Newcastle upon Tyne UK

25. Malformation Monitoring Centre Saxony‐Anhalt, Medical Faculty Otto‐von‐Guericke University Magdeburg Germany

26. Brittany Registry of Congenital Anomalies, CHU Rennes, Univ Rennes, Inserm, EHESP, IRSET (Institut de Recherche en Santé, Environnement et Travail) – UMR_S 1085 Rennes France

27. French West Indies Registry, Registre des Malformations des Antilles (REMALAN), Maison de la Femme de la Mère et de l'Enfant University Hospital of Martinique Fort‐de‐France France

28. Congenital Anomaly Register & Information Service for Wales (CARIS), Public Health Wales Swansea UK

29. University Hospital Southampton, Faculty of Medicine and Wessex Clinical Genetics Service, Princess Anne Hospital Southampton UK

30. Epidemiology Unit, Department of Preventive Medicine Poznan University of Medical Sciences Poznan Poland

31. OMNI‐Net Ukraine Birth Defects Program and Rivne Regional Medical Diagnostic Center Rivne Ukraine

Publisher

Wiley

Subject

Infectious Diseases,Dermatology

Reference33 articles.

1. Aplasia cutis cerebri with partial acrania—Total reconstruction in a severe case and review of the literature

2. Orphanet.Aplasia cutis congenita.https://www.orpha.net/consor/cgi‐bin/Disease_Search.php?lng=EN&data_id=3198&Disease_Disease_Search_diseaseGroup=1114&Disease_Disease_Search_diseaseType=ORPHA&Disease(s)/group%20of%20diseases=Aplasia‐cutis‐congenita&title=Aplasia%20cutis%20congenita&search=Disease_Search_Simple; (2019). Accessed 14 March 2022.

3. Aplasia cutis congenita: A clinical review and proposal for classification

4. Aplasia cutis congenita: report of 22 cases

5. Classification of aplasia cutis congenita: a 25‐year review of cases presenting to a tertiary paediatric dermatology department

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