Routine coagulation assays underestimate levels of antithrombin-dependent drugs but not of direct anticoagulant drugs in plasma from patients with cirrhosis

Author:

Potze Wilma1,Arshad Freeha1,Adelmeijer Jelle1,Blokzijl Hans2,van den Berg Arie P.2,Porte Robert J.3,Lisman Ton13

Affiliation:

1. Surgical Research Laboratory; Department of Surgery; University of Groningen; University Medical Centre Groningen; Groningen The Netherlands

2. Department of Gastroenterology; University of Groningen; University Medical Centre Groningen; Groningen The Netherlands

3. Section of Hepatobiliary Surgery and Liver Transplantation; Department of Surgery; University of Groningen; University Medical Centre Groningen; Groningen The Netherlands

Publisher

Wiley

Subject

Hematology

Reference19 articles.

1. Low-molecular-weight heparin in patients with advanced cirrhosis;Bechmann;Liver International: Official Journal of the International Association for the Study of the Liver,2011

2. Efficacy and safety of anticoagulation on patients with cirrhosis and portal vein thrombosis;Delgado;Clinical Gastroenterology and Hepatology: The Official Clinical Practice Journal of the American Gastroenterological Association,2012

3. Assessment of prognosis of cirrhosis;Durand;Seminars in Liver Disease,2008

4. Monitoring of heparin therapy: should heparin assays also reflect the patient's antithrombin concentration?;Holm;Thrombosis Research,1987

5. Comparison of the anticoagulant effect of a direct thrombin inhibitor and a low molecular weight heparin in an acquired antithrombin deficiency in children with acute lymphoblastic leukaemia treated with L-asparaginase: an in vitro study;Kuhle;British Journal of Haematology,2006

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