Structure/Activity Relationships of Polyfunctional Diterpenes of the Tigliane Type. A Pharmacophore Model for Protein-Kinase-C Activators Based on Structure/Activity Studies and Molecular Modeling of the Tumor Promoters 12-O-Tetradecanoylphorbol 13-Acetate and 3-O-Tetradecanoylingenol-Reference-Cited by-同舟云学术

Structure/Activity Relationships of Polyfunctional Diterpenes of the Tigliane Type. A Pharmacophore Model for Protein-Kinase-C Activators Based on Structure/Activity Studies and Molecular Modeling of the Tumor Promoters 12-O-Tetradecanoylphorbol 13-Acetate and 3-O-Tetradecanoylingenol

Published:1996-12 Issue:2 Volume:242 Page:417-427
ISSN:0014-2956
Container-title:European Journal of Biochemistry
language:en
Short-container-title:Eur J Biochem

Author:

Krauter Goetz,Lieth Claus-W.,Schmidt Rainer,Hecker Erich

Publisher

Wiley

Subject

Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1432-1033.1996.0417r.x/fullpdf

Reference51 articles.

1. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

2. The protein kinase C family

3. Protein kinase C isoenzymes: divergence in signal transduction?

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