The Retinoblastoma Protein: A Master Regulator of Cell Cycle, Differentiation and Apoptosis
Author:
Publisher
Wiley
Subject
Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1432-1033.1997.t01-2-00581.x/fullpdf
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1. Aberrations of p16Ink4 and retinoblastoma tumour-suppressor genes occur in distinct sub-sets of human cancer cell lines
2. Second Tumors in Nonirradiated Bilateral Retinoblastoma
3. Photoreceptor degeneration induced by the expression of simian virus 40 large tumor antigen in the retina of transgenic mice.
4. Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.
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