DNA Interactions of Bifunctional Dinuclear Platinum(II) Antitumor Agents
Author:
Publisher
Wiley
Subject
Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1432-1033.1997.00508.x/fullpdf
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1. Platinum-195 NMR kinetic and mechanistic studies of cis- and trans-diamminedichloroplatinum(II) binding to DNA
2. Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia
3. The dinuclear complex [{trans-PtCl(NH3)2}2{µ-H2N(CH2)6NH2}]Cl2forms a unique macrochelate intrastrand crosslink with d(GpG)
4. Formation of DNA Adducts by the Anticancer Drug Carboplatin: Different Nucleotide Sequence Preferences in Vitro and in Cells
5. DNA interstrand cross-links of trans-diamminedichloroplatinum(II) are preferentially formed between guanine and complementary cytosine residues.
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