Activation of the O-2-Generating NADPH Oxidase in a Semi-Recombinant Cell-Free System. Assessment of the Function of Rac in the Activation Process
Author:
Publisher
Wiley
Subject
Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1432-1033.1994.tb20084.x/fullpdf
Reference42 articles.
1. Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1
2. Reconstitution of neutrophil NADPH oxidase activity in the cell-free system by four components: p67-phox, p47-phox, p21rac1, and cytochrome b-245.
3. Activation of NADPH oxidase involves the dissociation of p21rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane
4. Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase.
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