Pseudomonas aeruginosa pyocyanin causes airway goblet cell hyperplasia and metaplasia and mucus hypersecretion by inactivating the transcriptional factor FoxA2

Author:

Hao Yonghua,Kuang Zhizhou,Walling Brent E.,Bhatia Shikha,Sivaguru Mayandi,Chen Yin,Gaskins H. Rex,Lau Gee W.

Publisher

Hindawi Limited

Subject

Virology,Immunology,Microbiology

Reference46 articles.

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3. Pseudomonas aeruginosa exotoxin pyocyanin causes cystic fibrosis airway pathogenesis;Caldwell;Am J Pathol,2009

4. Epidermal growth factor receptor activation by epidermal growth factor mediates oxidant-induced goblet cell metaplasia in human airway epithelium;Casalino-Matsuda;Am J Respir Cell Mol Biol,2006

5. SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production;Chen;J Clin Invest,2009

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