The frequency of sarcopenia has increased in patients with glomerulonephritis

Author:

Isiktas Okay1ORCID,Guzel Fatma Betul2ORCID,Ozturk Ilyas2ORCID,Topal Kenan3ORCID,Sahin Murat4ORCID,Altunoren Orcun2ORCID,Gungor Ozkan2ORCID

Affiliation:

1. Department of Internal Medicine Faculty of Medicine, Kahramanmaras Sutcu Imam University Kahramanmaras Turkey

2. Department of Nephrology Faculty of Medicine, Kahramanmaras Sutcu Imam University Kahramanmaras Turkey

3. Adana City Training and Research Hospital, Department of Family Medicine Health Sciences University Adana Turkey

4. Department of Endocrinology Faculty of Medicine, Kahramanmaras Sutcu Imam University Kahramanmaras Turkey

Abstract

AbstractAimSarcopenia is defined as the loss of muscle mass and muscle strength, and its frequency increases in kidney patients. However, sarcopenia frequency in patients with glomerulonephritis is unknown. The present study aimed to investigate the frequency of sarcopenia in patients with glomerulonephritis and compare the results with the healthy population for the first time in the literature.Patients and MethodsA total of 110 participants, including 70 patients previously diagnosed with glomerulonephritis and 40 healthy individuals, were included in the study. The diagnosis of sarcopenia was made based on the EWSGOP 2 Criteria.ResultsThe mean age of the glomerulonephritis patients group was 39.3 ± 1.5. In the anthropometric measurements of the patients, walking speed was low in 50 patients (71.4%), muscle strength was decreased in 44 patients (62.9%), and sarcopenia was detected in 10 patients (14.3%) according to the EWGSOP 2 Criteria. Considering the anthropometric measurements of the control group, sarcopenia was not detected in any of the subjects according to the EWGSOP 2 Criteria.ConclusionThe result of the present study revealed that the rate of sarcopenia was significantly higher in glomerulonephritis patients compared to the healthy population and that sarcopenia can also be observed even in middle age in this population. We think it would be beneficial for clinicians treating glomerulonephritis to be more careful regarding sarcopenia and keep these parameters in mind during treatment.

Publisher

Wiley

Subject

Nephrology,General Medicine

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3. An elusive consensus definition of sarcopenia impedes research and clinical treatment: A narrative review

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