The ketogenic diet component decanoic acid increases mitochondrial citrate synthase and complex I activity in neuronal cells

Author:

Hughes Sean David12,Kanabus Marta1,Anderson Glenn3,Hargreaves Iain P.4,Rutherford Tricia5,Donnell Maura O’5,Cross J. Helen6,Rahman Shamima17,Eaton Simon8,Heales Simon J. R.124

Affiliation:

1. Clinical and Molecular Genetics Unit; UCL Institute of Child Health; London UK

2. Chemical Pathology; Great Ormond Street Hospital for Children NHS Foundation Trust; London UK

3. Electron Microscopy Unit; Great Ormond Street Hospital, Foundation Trust; London UK

4. Neurometabolic Unit; National Hospital for Neurology and Neurosurgery; London UK

5. Vitaflo International; Liverpool UK

6. Neurosciences Unit; UCL Institute of Child Health; London UK

7. Metabolic Unit; Great Ormond Street Hospital Foundation Trust; London UK

8. Paediatric Surgery Unit; UCL Institute of Child Health; London UK

Funder

Great Ormond Street Hospital Children's Charity

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference37 articles.

1. Ketogenic diet. Update and application;Bahassan;Neurosciences (Riyadh),2006

2. Mitochondrial catalase and oxidative injury;Bai;Biol. Signals Recept.,2001

3. A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase;Beers;J. Biol. Chem.,1952

4. Diagnostic criteria for respiratory chain disorders in adults and children;Bernier;Neurology,2002

5. Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture;Bolaños;J. Neurochem.,1995

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