Pharmacokinetics of a single dose of <i>Aficamten</i> ( <scp>CK</scp> ‐274) on cardiac contractility in a <scp>A31P</scp> <i>MYBPC3</i> hypertrophic cardiomyopathy cat model-Reference-Cited by-同舟云学术

Pharmacokinetics of a single dose of Aficamten ( CK ‐274) on cardiac contractility in a A31P MYBPC3 hypertrophic cardiomyopathy cat model

Published:2022-11-16 Issue:1 Volume:46 Page:52-61
ISSN:0140-7783
Container-title:Journal of Veterinary Pharmacology and Therapeutics
language:en
Short-container-title:Vet Pharm & Therapeutics

Author:

Sharpe Ashley N.¹,Oldach Maureen S.¹,Kaplan Joanna L.¹,Rivas Victor¹,Kovacs Samantha L.¹^ORCID,Hwee Darren T.²^ORCID,Morgan Bradley P.²,Malik Fady I.²^ORCID,Harris Samantha P.³,Stern Joshua A.¹^ORCID

Affiliation:

1. Department of Medicine and Epidemiology, Davis, School of Veterinary Medicine University of California Davis California USA

2. Research and Non‐clinical Development Cytokinetics, Inc South San Francisco California USA

3. Department of Cellular and Molecular Medicine University of Arizona Tucson Arizona USA

Funder

Cytokinetics

Publisher

Wiley

Subject

General Veterinary,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jvp.13103

Reference29 articles.

1. Two-Dimensional Echocardiographic Assessment of the Feline Left Atrium

2. Small Molecules Acting on Myofilaments as Treatments for Heart and Skeletal Muscle Diseases

3. Emerging Medical Treatment for Hypertrophic Cardiomyopathy

4. Small-molecule inhibitors of myosin proteins

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