Mesenchymal stem cells deliver exogenous miR-21viaexosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration

Author:

Cheng Xiaofei12,Zhang Guoying3,Zhang Liang4,Hu Ying5,Zhang Kai1,Sun Xiaojiang1,Zhao Changqing1,Li Hua1,Li Yan Michael2,Zhao Jie1ORCID

Affiliation:

1. Department of Orthopaedic Surgery; Shanghai Key Laboratory of Orthopaedic Implants; Shanghai Ninth People's Hospital; Shanghai JiaoTong University School of Medicine; Shanghai China

2. Department of Neurosurgery; University of Rochester School of Medicine and Dentistry; Rochester NY USA

3. Department of Orthopedics; The General Hospital of Chinese People's Liberation Army; Beijing China

4. Department of Orthopedics; Subei People's Hospital of Jiangsu Province; Clinical Medical College of Yangzhou University; Yangzhou Jiangsu China

5. Department of Toxicity Evaluation; Shanghai Municipal Center for Disease Control and Prevention; Shanghai China

Funder

National Natural Science Foundation of China

The Industry-Academy-Research Cooperation Project of Shanghai Science and Technology Committee

The Department Integration Foundation of Shanghai Ninth People's Hospital

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

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