Metformin protects against intestinal barrier dysfunction via AMPKα1-dependent inhibition of JNK signalling activation
Author:
Affiliation:
1. State Key Laboratory of Organ Failure Research; Guangdong Provincial Key Laboratory of Gastroenterology; Department of Gastroenterology; Nanfang Hospital; Southern Medical University; Guangzhou Guangdong China
Funder
National Natural Science Foundation of China
Publisher
Wiley
Subject
Cell Biology,Molecular Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jcmm.13342/fullpdf
Reference49 articles.
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2. Epithelial barriers in intestinal inflammation;John;Antioxid Redox Signal,2011
3. TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation;Ma;Am J Physiol Gastrointest Liver Physiol,2004
4. Tight junctions/adherens junctions: basic structure and function;Niessen;J Invest Dermatol,2007
5. JAM-A regulates permeability and inflammation in the intestine in vivo;Laukoetter;J Exp Med,2007
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