The natural agent rhein induces β-catenin degradation and tumour growth arrest

Author:

Liu Shu1,Wang Jiao2,Shao Ting1,Song Peiying1,Kong Qingbin1,Hua Hui3,Luo Ting4,Jiang Yangfu1ORCID

Affiliation:

1. State Key Laboratory of Biotherapy; Section of Oncogene; Cancer Center; West China Hospital; Sichuan University; Chengdu China

2. School of Basic Medicine; Chengdu University of Traditional Chinese Medicine; Chengdu China

3. Laboratory of Stem Cell Biology; West China Hospital; Sichuan University; Chengdu China

4. Cancer Center; West China Hospital; Chengdu China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Reference46 articles.

1. Rhein lysinate induces apoptosis in breast cancer SK-Br-3 cells by inhibiting HER-2 signal pathway;Lin;Acta Pharm Sin,2008

2. Rhein lysinate suppresses the growth of breast cancer cells and potentiates the inhibitory effect of taxol in athymic mice;Lin;Anticancer Drug,2009

3. Rhein induces apoptosis and cell cycle arrest in human hepatocellular carcinoma BEL-7402 cells;Shi;Am J Chinese Med,2008

4. Rhein inhibits the growth and induces the apoptosis of Hep G2 cells;Kuo;Planta Med,2004

5. Rhein induces apoptosis through induction of endoplasmic reticulum stress and Ca2 + -dependent mitochondrial death pathway in human nasopharyngeal carcinoma cells;Lin;Anticancer Res,2007

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