Neuromelanin-sensitive magnetic resonance imaging features of the substantia nigra and locus coeruleus in de novo Parkinson's disease and its phenotypes

Author:

Wang J.12,Li Y.3,Huang Z.3,Wan W.3,Zhang Y.4,Wang C.3,Cheng X.3,Ye F.12,Liu K.12,Fei G.3,Zeng M.12,Jin L.3ORCID

Affiliation:

1. Department of Radiology; Zhongshan Hospital; Fudan University; Shanghai China

2. Shanghai Medical Imaging Institute; Shanghai China

3. Department of Neurology; Zhongshan Hospital; Fudan University; Shanghai China

4. MR Research; GE Healthcare; Shanghai China

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Reference42 articles.

1. Staging of brain pathology related to sporadic Parkinson's disease;Braak;Neurobiol Aging,2003

2. On the origin and significance of neuromelanin;Graham;Arch Pathol Lab Med,1979

3. Brain pigment and its relation to brain catecholamines;Marsden;Lancet,1965

4. Studies on neuromelanin. I. A melanin system in the human adult brainstem;Bazelon;Neurology,1967

5. Neuromelanin can protect against iron-mediated oxidative damage in system modeling iron overload of brain aging and Parkinson's disease;Zecca;J Neurochem,2008

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