Changing landscape of alcohol‐associated liver disease in younger individuals, women, and ethnic minorities

Author:

Arab Juan P123ORCID,Dunn Winston4ORCID,Im Gene5,Singal Ashwani K.67ORCID

Affiliation:

1. Division of Gastroenterology, Department of Medicine, Schulich School of Medicine Western University & London Health Sciences Centre London Ontario Canada

2. Department of Epidemiology and Biostatistics, Schulich School of Medicine Western University London Ontario Canada

3. Departamento de Gastroenterologia, Escuela de Medicina Pontificia Universidad Catolica de Chile Santiago Chile

4. Division of Gastroenterology and Hepatology, Department of Medicine University of Kansas Medical Center Kansas City Kansas USA

5. Division of Gastroenterology and Hepatology, Department of Medicine Mount Sinai Medical School New York New York USA

6. Division of Gastroenterology and Hepatology, Department of Medicine University of Louisville Louisville Kentucky USA

7. Health Research, VA Medical Center Sioux Falls South Dakota USA

Abstract

AbstractAlcohol use is the most important determinant of the development of alcohol‐associated liver disease (ALD) and of predicting long‐term outcomes in those with established liver disease. Worldwide, the amount, type, and pattern of use of alcohol vary. Alcohol use and consequent liver disease have been increasing in certain ethnic groups especially Hispanics and Native Americans, likely due to variations in genetics, cultural background, socio‐economic status, and access to health care. Furthermore, the magnitude and burden of ALD have been increasing especially in the last few years among females and young adults who are at the prime of their productivity. It is critical to recognize the problem and care for these patients integrating cultural aspects in liver clinics. At the federal level, a societal approach is needed with the implementation of public health policies aiming to reduce alcohol consumption in the community. By addressing these challenges and promoting awareness, we can strive to reduce the burden of ALD, especially in high‐risk demographic groups to improve their long‐term health outcomes. Finally, we need studies and quality research examining these changing landscapes of demographics in ALD as a basis for developing therapeutic targets and interventions to reduce harmful drinking behaviours in these high‐risk demographic groups.

Publisher

Wiley

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