Affiliation:
1. Faculty of Life Science and Technology Kunming University of Science and Technology Kunming China
2. Department of Gynecology The First People’s Hospital of Yunnan Province Kunming China
Abstract
Abstract
A new type of nitrogen and chloride co-doped carbon dots (N/Cl-CDs) based on choline chloride–urea–glycine ternary deep eutectic solvents (DESs) was synthesized using a one-step hydrothermal method. The prepared N/Cl-CDs exhibited oxidase-like activity and excellent antibacterial activity against Escherichia coli, Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). The addition of silver nanoparticles (Ag NPs) (i.e. N/Cl-CDs + Ag NPs) to the N/Cl-CDs also significantly enhanced the oxidase and antibacterial activities. The nanocomposite (1·8 mg ml−1) completely inactivated 105 CFU per ml of MRSA in 90 min. E. coli and S. aureus were labelled with the N/Cl-CDs, enabling multicolour fluorescence imaging at different excitation wavelengths. The nanocomposites have high antibacterial efficiency as a new bactericidal agent, as well as application potential with good biocompatibility and low toxicity.
Funder
Kunming University of Science and Technology Analytical Testing Fund
Talent Development Program of Yunnan province
Open project of Yunnan Provincial Reproductive and Obstetrics and Gynecology Clinical Medicine Center
Basic research program of Yunnan province
Publisher
Oxford University Press (OUP)
Subject
Applied Microbiology and Biotechnology
Cited by
4 articles.
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