Nobiletin, a Polymethoxy Flavonoid, Reduced Endothelin-1 Plus SCF-Induced Pigmentation in Human Melanocytes

Author:

Kim Hyo Jung1,Yonezawa Takayuki1,Teruya Toshiaki2,Woo Je-Tae13,Cha Byung-Yoon1

Affiliation:

1. Research Institute for Biological Functions; Chubu University; Kasugai Aichi Japan

2. Faculty of Education; University of the Ryukyus; Nishihara Okinawa Japan

3. Department of Research and Development; Erina Co., Inc.; Minato-ku Tokyo Japan

Publisher

Wiley

Subject

Physical and Theoretical Chemistry,General Medicine,Biochemistry

Reference49 articles.

1. Chemical and instrumental approaches to treat hyperpigmentation;Briganti;Pigment Cell Melanoma Res.,2003

2. Endothelins secreted from human keratinocytes are intrinsic mitogens for human melanocyte;Imokawa;J. Biol. Chem.,1992

3. Endothelin-1 as a new melanogen: coordinated expression of its gene and the tyrosinase gene in UVB-exposed human epidermis;Imokawa;J. Invest. Dermatol.,1995

4. Mitogenic melanogenic stimulation of normal human melanocytes by melanotropic peptides;Abdel-Malek;Proc. Natl Acad. Sci. USA,1995

5. Binding of melanotropic hormones to the melanocortin receptor MC1R on human melanocytes stimulates proliferation and melanogenesis;Suzuki;Endocrinology,1996

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