Time to change the reference ranges of children's physiological observations in emergency care? A prospective study

Author:

Brennan Louise12,Heal Calvin3,Brown Stephen4,Roland Damian56,Rowland Andrew G789ORCID

Affiliation:

1. Lead Employer St Helens and Knowsley Teaching Hospitals NHS Trust St Helens United Kingdom

2. Medical School Lancaster University Lancaster United Kingdom

3. School of Health Sciences The University of Manchester Manchester United Kingdom

4. Research and Innovation Department The Northern Care Alliance NHS Foundation Trust Salford United Kingdom

5. Paediatric Emergency Medicine Leicester Academic (PEMLA) group, Children's Emergency Department Leicester Royal Infirmary Leicester United Kingdom

6. SAPPHIRE Group, Health Sciences Leicester University Leicester United Kingdom

7. Department of Community Paediatrics Manchester University NHS Foundation Trust Manchester United Kingdom

8. School of Health and Society The University of Salford Salford United Kingdom

9. Community Paediatrics Manchester Local Care Organisation Manchester United Kingdom

Abstract

AimHigh heart and respiratory rates are key indicators in many published guidelines to identify and treat serious bacterial infection and sepsis in children, but the credibility of evidence underpinning what is considered abnormal is questionable. This study established the distribution of heart and respiratory rates of children using a large data set to inform debate on what the ‘normal’ range of these should look like. The primary aim was to compare the distribution of heart and respiratory rates measured in children recruited from non‐tertiary emergency care settings with those published by Advanced Paediatric Life Support (APLS). The secondary aim was to compare the distribution of this study's data set to other national guidance on what constitutes a severe (high‐risk) measurement and previously published data sets.MethodProspective study using anonymised patient data, extracted from electronic patient records of children and young people 0–16 years, recruited from three Emergency Departments and one Urgent Care Centre in Northwest England, UK.ResultsHeart and respiratory rates, including the reporting of values at certain centiles and comparisons of averages. Distribution of heart and respiratory rate were consistently higher than those used by the APLS guidance, resulting in a large proportion exceeding the ‘severe’ cut‐offs proposed. This varied greatly by age.ConclusionsThis study's data set suggests normal heart rate ranges proposed by the APLS and others is too low and therefore ‘abnormal’ measurements encompass too large a proportion. The respiratory rate of this data set was more consistent with the guidelines and other published data sets.

Publisher

Wiley

Subject

Pediatrics, Perinatology and Child Health

Reference18 articles.

1. The UK Sepsis Trust.About Sepsis. Available from:https://sepsistrust.org/about/about-sepsis/[accessed 2 December 2021].

2. Royal College of Nursing.Sepsis; 2021. Available from:https://www.rcn.org.uk/clinical-topics/infection-prevention-and-control/sepsis[accessed 2 December 2021].

3. Office for National Statistics.Child Mortality (Death Cohort) Tables in England and Wales; 2021. Available from:https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/datasets/childmortalitystatisticschildhoodinfantandperinatalchildhoodinfantandperinatalmortalityinenglandandwales[accessed 2 December 2021].

4. Sepsis Alliance.Children; 2021. Available from:https://www.sepsis.org/sepsisand/children/[accessed 2 December 2021].

5. NHS England.Improving Outcomes for Patients with Sepsis. A Cross‐System Action Plan; 2015. Available from:https://www.england.nhs.uk/wp-content/uploads/2015/08/Sepsis-Action-Plan-23.12.15-v1.pdf[accessed 2 December 2021].

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