Collapse of the native structure caused by a single amino acid exchange in human NAD (P)H:quinone oxidoreductase 1-Reference-Cited by-同舟云学术

Collapse of the native structure caused by a single amino acid exchange in human NAD (P)H:quinone oxidoreductase 1

Published:2014-09-19 Issue:20 Volume:281 Page:4691-4704
ISSN:1742-464X
Container-title:The FEBS Journal
language:en
Short-container-title:FEBS J

Author:

Lienhart Wolf‐Dieter¹,Gudipati Venugopal¹,Uhl Michael K.²,Binter Alexandra¹,Pulido Sergio A.³,Saf Robert⁴,Zangger Klaus³,Gruber Karl²,Macheroux Peter¹

Affiliation:

1. Institute of Biochemistry Graz University of Technology Austria

2. Institute of Molecular Biosciences University of Graz Austria

3. Institute of Chemistry University of Graz Austria

4. Institute of Chemistry and Technology of Materials Graz University of Technology Austria

Funder

Austrian Fonds zur Förderung der wissenschaftlichen Forschung (FWF)

PhD program ‘Molecular Enzymology’

NAWI Graz

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/febs.12975

Reference36 articles.

1. NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

2. Regulation of p53 stability and p53‐dependent apoptosis by NADH quinone oxidoreductase 1;Asher G;Proc Natl Acad Sci USA,2001

3. A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73

4. NAD(P)H quinone oxidoreductase 1 inhibits the proteasomal degradation of the tumour suppressor p33ING1b

5. NRH:Quinone Oxidoreductase 2 and NAD(P)H:Quinone Oxidoreductase 1 Protect Tumor Suppressor p53 against 20S Proteasomal Degradation Leading to Stabilization and Activation of p53

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