Design of potent B-RafV600Einhibitors by multiple copy simulation search strategy-Reference-Cited by-同舟云学术

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Design of potent B-RafV600Einhibitors by multiple copy simulation search strategy

Published:2017-12-15 Issue:2 Volume:91 Page:567-574
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Wang Ze-Feng¹,Wang Peng-Fei¹,Ma Jun-Ting¹,Chai Ying-Zi¹,Hu Hui-Min¹,Gao Wen-Long¹,Wang Zhong-Chang¹,Wang Bao-Zhong¹,Zhu Hai-Liang¹^ORCID

Affiliation:

1. State Key Laboratory of Pharmaceutical Biotechnology; Nanjing University; Nanjing China

Funder

National Science & Technology

National Undergraduate Innovation Program

National Natural Science Foundation of China

Research Innovation Program for College Graduates of Jiangsu Province

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.13121/fullpdf

Reference22 articles.

1. Pathological roles of MAPK signaling pathways in human diseases

2. The ASK1-MAP Kinase Signaling in ER Stress and Neurodegenerative Diseases

3. Discovery of 1-(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a Pan-RAF Inhibitor with Minimal Paradoxical Activation and Activity against BRAF or RAS Mutant Tumor Cells

4. Induction of COX-2-PGE2 synthesis by activation of the MAPK/ERK pathway contributes to neuronal death triggered by TDP-43-depleted microglia

5. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance

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2. Virtual screening, pharmacokinetic, and DFT studies of anticancer compounds as potential kinase inhibitors;Journal of Taibah University Medical Sciences;2023-10

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4. Design, synthesis, and biological evaluation of novel imidazole derivatives possessing terminal sulphonamides as potential BRAFV600Einhibitors;Bioorganic Chemistry;2021-01

5. Systemic review on B-RafV600E mutation as potential therapeutic target for the treatment of cancer;European Journal of Medicinal Chemistry;2020-11

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