Efficacy and safety of brodalumab in patients with generalized pustular psoriasis and psoriatic erythroderma: results from a 52-week, open-label study

Author:

Yamasaki K.1,Nakagawa H.2,Kubo Y.3,Ootaki K.4,

Affiliation:

1. Department of Dermatology; Tohoku University Graduate School of Medicine; Tohoku University Hospital; 1-1 Seiryo-cho Aoba-ku Sendai Miyagi 980-8574 Japan

2. Department of Dermatology; The Jikei University School of Medicine; Tokyo Japan

3. Department of Dermatology; Institute of Biomedical Sciences; Tokushima University Graduate School; Tokushima Japan

4. Kyowa Hakko Kirin Co. Ltd; Tokyo Japan

Funder

Kyowa Hakko Kirin

Publisher

Wiley

Subject

Dermatology

Reference24 articles.

1. Practice guidelines 2010 for generalized pustular psoriasis (GPP): treatment guidelines incorporating TNF-α inhibitor;Iwatsuki;Jpn J Dermatol,2010

2. Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells;Lowes;J Invest Dermatol,2008

3. Serum and tissue levels of IL-17 in different clinical subtypes of psoriasis;Yilmaz;Arch Dermatol Res,2012

4. Increased expression of IL-17A and limited involvement of IL-23 in patients with palmo-plantar (PP) pustular psoriasis or PP pustulosis; results from a randomised controlled trial;Bissonnette;J Eur Acad Dermatol Venereol,2014

5. Bullous pemphigoid followed by pustular psoriasis showing Th1, Th2, Treg and Th17 immunological changes;Yasukawa;Eur J Dermatol,2009

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