Translational aspects of cytochrome P450‐mediated drug–drug interactions: A case study with clopidogrel-Reference-Cited by-同舟云学术

Translational aspects of cytochrome P450‐mediated drug–drug interactions: A case study with clopidogrel

Published:2021-09-25 Issue:S1 Volume:130 Page:48-59
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharma Tox

Author:

Tornio Aleksi¹²^ORCID,Filppula Anne M.³⁴⁵^ORCID,Backman Janne T.⁴⁵^ORCID

Affiliation:

1. Integrative Physiology and Pharmacology, Institute of Biomedicine University of Turku Turku Finland

2. Unit of Clinical Pharmacology Turku University Hospital Turku Finland

3. Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering Åbo Akademi University Turku Finland

4. Individualized Drug Therapy Research Program, Faculty of Medicine University of Helsinki Helsinki Finland

5. Department of Clinical Pharmacology University of Helsinki and Helsinki University Hospital Helsinki Finland

Funder

Sigrid Juséliuksen Säätiö

Academy of Finland

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcpt.13647

Reference55 articles.

1. US Food and Drug Administration Center for Drug Evaluation and Research.In vitro drug interaction studies—cytochrome P450 enzyme‐ and transporter‐mediated drug interactions guidance for industry.2020.https://www.fda.gov/regulatory-information/search-fda-guidance-documents/vitro-drug-interaction-studies-cytochrome-p450-enzyme-and-transporter-mediated-drug-interactionsAccessed 15 March 2021.

2. US Food and Drug Administration Center for Drug Evaluation and ResearchClinical drug interaction studies—study design data analysis and clinical implications guidance for industry. 2020.https://www.fda.gov/regulatory‐information/search‐fda‐guidance‐documents/clinical‐drug‐interaction‐studies‐cytochrome‐p450‐enzyme‐and‐transporter‐mediated‐drug‐interactionsAccessed 15 March 2021.

3. European Medicines Agency.Guideline on the investigation of drug interactions.2012.https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-investigation-drug-interactions-revision-1_en.pdfAccessed 15 March 2021.

4. In vitro and in vivo methods to assess pharmacokinetic drug– drug interactions in drug discovery and development

5. Clopidogrel as a Perpetrator of Drug–Drug Interactions: A Challenge for Quantitative Predictions?

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