The catalytic topoisomerase II inhibitor dexrazoxane induces DNA breaks, ATF3 and the DNA damage response in cancer cells
Author:
Affiliation:
1. Institute of Pharmacology; Medical Center of the University Mainz; Mainz Germany
2. Institute of Toxicology; Medical Center of the University Mainz; Mainz Germany
Funder
Deutsche Forschungsgemeinschaft
Publisher
Wiley
Subject
Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.13046/fullpdf
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4. Anthracyclines, HER2, and TOP2A: the verdict;Bonnefoi;Lancet Oncol,2011
5. Topoisomerase levels determine chemotherapy response in vitro and in vivo;Burgess;Proc Natl Acad Sci U S A,2008
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